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53 Ebola-blocking drugs identified among existing medications

Thu, 18 Dec 2014 08:00:00 PST

Using high-speed screening technology, researchers have identified 53 drugs - including some antihistamines and antidepressants - that may prevent Ebola from entering human cells.

Intravenous vs. oral antibiotics for osteomyelitis, serious bone infections in children

Thu, 18 Dec 2014 01:00:00 PST

Children with osteomyelitis (a serious bacterial bone infection) who were discharged from the hospital to complete several weeks of outpatient antibiotic therapy with an oral medication did not...

Bacterial biofilms found in colon cancer patients could be used as a clinical diagnostic tool

Thu, 18 Dec 2014 00:00:00 PST

Since the first "catalog" of the normal bacterial makeup of the human body was published in 2012, numerous connections between illness and disturbances in the human microbiota have been found.

Ebola expert confident of Australian consensus

Wed, 17 Dec 2014 13:00:00 PST

The infectious diseases expert charged with finding consensus nationally on Ebola virusguidelines and recommendations says she is pleased with the progress made so far.

Universal dengue vaccine steps closer with antibodies discovery

Wed, 17 Dec 2014 03:00:00 PST

In a move toward a universal dengue vaccine, researchers report finding a class of antibodies that can neutralize all four types of virus produced from human or mosquito cells.

Researchers identify method to assess urinary tract infection risk in women after pelvic-floor surgery

Wed, 17 Dec 2014 00:00:00 PST

Researchers at Loyola University Chicago Stritch School of Medicine may have identified a way to assess who is at risk for developing a urinary tract infection (UTI) following pelvic-floor surgery.

Study highlights importance of nutritional immunity in fighting infectious disease

Wed, 17 Dec 2014 00:00:00 PST

Examination of DNA from 21 primate species - from squirrel monkeys to humans - exposes an evolutionary war against infectious bacteria over iron that circulates in the host's bloodstream.

Better understanding of how viruses replicate and role of telomeres in stopping viruses

Wed, 17 Dec 2014 00:00:00 PST

A team of scientists, led by researchers at The Wistar Institute, has found that an infection with herpes simplex virus 1 (HSV-1) causes rearrangements in telomeres, small stretches of DNA that serve...

Epidemic status unlikely to be reached by Middle East respiratory syndrome coronavirus

Wed, 17 Dec 2014 00:00:00 PST

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus, with the first case reported in 2012.

How gut bacterial resources are hijacked to promote intestinal illnesses

Tue, 16 Dec 2014 00:00:00 PST

UT Southwestern Medical Center microbiologists have identified key bacteria in the gut whose resources are hijacked to spread harmful foodborne E. coli infections and other intestinal illnesses.

Genes expressed during urinary tract infections suggest next-generation treatment

Tue, 16 Dec 2014 00:00:00 PST

Urinary tract infections can occur with no apparent cause, and as effectiveness of antibiotics fades, treating them is also becoming less predictable.

Lyssavirus notification, treatment guidelines appropriate

Mon, 15 Dec 2014 02:00:00 PST

The rare but fatal consequences of Australian bat lyssavirus (ABLV) infection means guidelines recommending that all exposures be notified, and describing post-exposure prophylaxis remain...

Dental divide harming Australians as decay sets in

Mon, 15 Dec 2014 02:00:00 PST

It is time medical and dental interests combined to combat a rise in tooth decay and oral diseasein Australians, says the author of a Perspective published in the Medical Journal of Australia.

Simple steps can safeguard against Ebola transmission through organ donation

Mon, 15 Dec 2014 02:00:00 PST

While serious infections can be transmitted from donated organs, the risk of passing Ebola virus disease from an organ donor to a recipient is extremely small.

Molecular decoys help overcome drug resistance

Mon, 15 Dec 2014 00:00:00 PST

Efflux pumps are surface proteins that prevent antimicrobial drugs from getting a foothold in a bacterial cell by identifying and pumping them out of the cell.

Tracking neutrophil motility patterns could provide early diagnosis of sepsis in patients with major burns

Sat, 13 Dec 2014 00:00:00 PST

A team of Massachusetts General Hospital (MGH) investigators has identified what may be a biomarker predicting the development of the dangerous systemic infection sepsis in patients with serious...

Study links Parkinson's disease to gut bacteria

Fri, 12 Dec 2014 03:00:00 PST

A new study finds that people with Parkinson's disease have a different mix of gut bacteria to healthy counterparts, suggesting this might be useful for diagnosis or treatment.

Study indicates target for future drugs for Ebola, measles, RSV

Fri, 12 Dec 2014 03:00:00 PST

University of Utah researchers ran biochemical analysis and computer simulations of a livestock virus to discover a likely and exotic mechanism to explain the replication of related viruses such as...

Drug developed at Pitt proves effective against antibiotic-resistant 'superbugs'

Fri, 12 Dec 2014 02:00:00 PST

A treatment pioneered at the University of Pittsburgh Center for Vaccine Research (CVR) is far more effective than traditional antibiotics at inhibiting the growth of drug-resistant bacteria...

New study shows increase in raw milk-associated outbreaks

Fri, 12 Dec 2014 02:00:00 PST

A study published in the Centers for Disease Control and Prevention's Emerging Infectious Diseases Journal shows that the average annual number of outbreaks due to drinking raw (unpasteurized) milk...